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[Pancreatic carcinoid].

Radoje Colović¹, Marjan Micev, Natasa Colović

¹Institute of Digestive Diseases, Clinical Centre of Serbia, Belgrade.

Srpski Arhiv Za Celokupno Lekarstvo

|October 25, 2002

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Pancreatic carcinoid tumors are rare and often malignant. Surgical excision offers the best chance for recovery, as demonstrated in a successful case of a patient with carcinoid syndrome.

Area of Science:

Endocrinology
Oncology
Gastroenterology

Background:

Carcinoid tumors originate from neuroendocrine cells and are exceptionally rare in the pancreas, with fewer than 50 reported cases.
These tumors, also known as pancreatic serotoninomas, can cause carcinoid syndrome but its absence does not rule out their presence.
Pancreatic carcinoid tumors are frequently malignant, with over 50% of patients presenting with metastases at diagnosis, complicating surgical options.

Observation:

A 57-year-old woman presented with carcinoid syndrome due to a malignant pancreatic head carcinoid tumor.
The patient had no liver or distant metastases, allowing for curative surgical intervention.
The tumor was successfully removed via pylorus-preserving cephalic duodenopancreatectomy with radical lymphadenectomy.

Findings:

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Histologic and immunohistochemical analyses confirmed the diagnosis of pancreatic carcinoid tumor.
The patient experienced complete symptom resolution following the surgical procedure.
The patient remained symptom-free for over eight months post-surgery.

Implications:

This case highlights that pancreatic carcinoid tumors, though rare, can be effectively treated with radical surgery.
Successful surgical excision, even in the presence of carcinoid syndrome, can lead to long-term survival and symptom relief.
Early diagnosis and surgical intervention are crucial for improving outcomes in patients with pancreatic carcinoid tumors.