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Prolonged ulcerative laryngitis.

Birgit Rakel1, Joseph R Spiegel, Robert Thayer Sataloff

  • 1American Institute for Voice and Ear Research Philadelphia, Pennsylvania, USA.

Journal of Voice : Official Journal of the Voice Foundation
|October 25, 2002
PubMed
Summary

A previously undescribed clinical syndrome of prolonged hoarseness and laryngeal inflammation affects young, healthy individuals, often following an upper respiratory infection. This condition can persist for up to a year despite medical treatment.

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Area of Science:

  • Otolaryngology
  • Laryngology
  • Internal Medicine

Background:

  • Acute and prolonged laryngitis are common diagnoses managed by primary care physicians.
  • Persistent symptoms despite treatment prompt referral to an otolaryngologist.

Purpose of the Study:

  • To describe a previously unrecognized clinical syndrome characterized by prolonged hoarseness, laryngeal inflammation, and vocal fold ulceration.
  • To highlight the features of this entity in a review of 14 patients.

Main Methods:

  • Retrospective review of 14 patients presenting with a specific constellation of laryngeal symptoms.
  • Analysis of patient demographics, medical history, and treatment outcomes.

Main Results:

  • A syndrome of prolonged hoarseness, laryngeal inflammation, and vocal fold ulceration was identified.

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  • Affected patients were often young, nonsmokers, and nondrinkers, with preceding or concurrent upper respiratory infections.
  • Symptoms persisted for up to one year despite aggressive medical therapy.

    • Conclusions:

    • A distinct clinical entity of prolonged laryngitis with vocal fold ulceration has been recognized.
    • This syndrome may affect young, healthy individuals and can be refractory to standard medical interventions.