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Updated: Sep 28, 2026
Thermal Ablation for the Treatment of Abdominal Tumors
Published on: March 7, 2011
Chemical-shift MR imaging of acetic acid during percutaneous chemical ablation therapy: preliminary work
David A Roberts1, Marc A Rosen, Timothy W I Clark
1Department of Radiology, University of Pennsylvania Medical Center, 3400 Spruce Street, Philadelphia, Pennsylvania 19104-4283, USA. roberst@rad.upenn.edu
Abstract:
The purpose of this study was to test the hypothesis that chemical-shift magnetic resonance (MR) imaging may be used to map the distribution of acetic acid during percutaneous chemical ablation procedures. Chemical-shift MR imaging was performed with use of standard methods on a 1.5-T scanner. Phantom and ex-vivo data demonstrated focal increases in the observed signal in chemical-shift MR imaging that correlate well with the site of injection. Preliminary study in a patient with hepatoma revealed focal signal at the injection site. These preliminary results suggest that chemical-shift MR imaging may be used to visualize acetic acid distribution during percutaneous chemical ablation procedures.
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