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[Postoperative nausea and vomiting--pathophysiology, prophylaxis and treatment]
1Klinik und Poliklinik für Anästhesiologie, Universitätsklinikum Hamburg-Eppendorf, Germany.
Laryngo- Rhino- Otologie
|October 25, 2002
Summary
Postoperative nausea and vomiting (PONV) is a common complication, especially after ear or tonsil surgery. Prophylactic antiemetic therapy, particularly 5-HT 3 receptor antagonists, is recommended for high-risk patients to prevent severe outcomes.
Area of Science:
- Anesthesiology and Perioperative Medicine
- Gastroenterology
- Otolaryngology
Context:
- Postoperative nausea and vomiting (PONV) is a frequent complication following surgical procedures.
- High incidence rates (up to 70%) of PONV are observed in patients undergoing middle ear surgery or adenotonsillectomy.
- PONV can lead to significant postoperative complications, increased healthcare costs, and patient distress.
Purpose:
- To review the pathophysiology of PONV.
- To discuss prophylactic strategies for PONV.
- To outline treatment options for PONV, with a focus on ENT surgery.
Summary:
- PONV is a common and costly complication after surgery, particularly ENT procedures.
- 5-HT 3 receptor antagonists demonstrate high efficacy in preventing and managing PONV.
- Prophylactic antiemetic therapy is crucial for patients at high risk of developing PONV.
Impact:
- Provides a comprehensive overview of PONV management in the context of ENT surgery.
- Highlights the importance of prophylactic antiemetic therapy for at-risk individuals.
- Informs clinical practice regarding the effective use of 5-HT 3 receptor antagonists for PONV.