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Normal splenic volume in adults by computed tomography.
Junichi Kaneko1, Yasuhiko Sugawara, Yuichi Matsui
1Artificial Organ and Transplantation Division, Department of Surgery, Graduate School of Medicine, University of Tokyo, Tokyo, Japan.
Hepato-Gastroenterology
|October 26, 2002
Summary
Spleen size in adults varies, with age being a significant factor. This study provides data to help diagnose enlarged spleen (splenomegaly).
Area of Science:
- Anatomy
- Radiology
- Medical Imaging
Background:
- Spleen size variations can indicate health status.
- Understanding normal spleen dimensions is crucial for clinical diagnosis.
Purpose of the Study:
- To investigate spleen size variations in adult populations.
- To identify factors influencing spleen volume, such as age and body composition.
Main Methods:
- Computed tomography (CT) was used to measure spleen volume in 150 healthy liver transplant donors.
- Statistical analysis explored correlations between spleen volume and demographic/anthropometric data.
Main Results:
- The average spleen volume was 112 cm³, with a range of 32–209 cm³.
- Spleen volume demonstrated a significant positive correlation with age (R = 0.36, p = 0.0002).
- No significant correlation was found between spleen volume and body weight or body surface area; gender did not influence spleen size.
Conclusions:
- Age-stratified normal ranges for spleen volume are recommended.
- This data can aid in the accurate diagnosis of splenomegaly.