Species sensitivity distributions: data and model choice
J R Wheeler1, E P M Grist, K M Y Leung
1School of Biological Sciences, University of London, Egham, Surrey, UK. j.wheeler@rhul.ac.uk
Abstract:
Species sensitivity distributions (SSDs) are increasingly incorporated into ecological risk assessment procedures. Although these new techniques offer a more transparent approach to risk assessment they demand more and superior quality data. Issues of data quantity and quality are especially important for marine datasets that tend to be smaller (and have fewer standard test methods) when compared with freshwater data. An additional source of uncertainty when using SSDs is appropriate selection from the range of methods used in their construction. We show through examples the influence of data quantity, data quality, and choice of model. We then show how regulatory decisions may be affected by these factors.
Related Concept Videos
Distributions to Estimate Population Parameter
Choosing Between z and t Distribution
Dose-Response Relationship: Selectivity and Specificity
Mechanistic Models: Compartment Models in Individual and Population Analysis
Pharmacokinetic Models: Comparison and Selection Criterion
Physiological models take a detailed approach by considering specific molecular processes. They can predict drug distribution, metabolism, and elimination changes, providing a comprehensive understanding of how drugs interact with the body.
Parametric Survival Analysis: Weibull and Exponential Methods
Weibull Distribution
The Weibull distribution is a flexible model used in parametric survival analysis. It can handle both increasing and decreasing hazard rates, depending on its shape parameter...


