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Updated: Sep 28, 2026

Catalytic Reactions at Amine-Stabilized and Ligand-Free Platinum Nanoparticles Supported on Titania During Hydrogenation of Alkenes and Aldehydes
Published on: June 24, 2022
Air-stable catalysts for highly efficient and enantioselective hydrogenation of aromatic ketones
Jing Wu1, Hua Chen, Waihim Kwok
1Open Laboratory of Chirotechnology of the Institute of Molecular Technology for Drug Discovery and Synthesis, Hung Hom, Kowloon, Hong Kong.
Abstract:
A series of chiral trans-[RuCl(2)(dipyridylphosphine)(1,2-diamine)] complexes have been synthesized and characterized by NMR and single-crystal X-ray diffraction studies. These Ru complexes combined with (CH(3))(3)COK in 2-propanol formed a very effective catalyst system for the hydrogenation of a diverse range of simple aromatic ketones with high activity (substrate-to-catalyst ratio up to 100 000) and excellent enantioselectivity (up to >99.9%). The catalyst system was also found to be stable in solution even under a normal atmosphere.
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