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New marine diterpenoids from the Okinawan soft coral Clavularia koellikeri
Makoto Iwashima1, Yuuki Matsumoto, Yosuke Takenaka
1Laboratory of Bioorganic Chemistry, School of Life Science, Tokyo University of Pharmacy and Life Science, Horinouchi, Hachioji, Japan.
Journal of Natural Products
|October 26, 2002
Abstract:
Chemical investigation of the Okinawan soft coral Clavularia koellikeri resulted in the isolation of two new cembrane diterpenoids (1 and 2) and one new dollabelane diterpenoid, 3. Their structures were determined on the basis of the results of spectroscopic analysis. Compounds 1 and 3 were examined for in vitro growth-inhibition effects toward tumor cells.