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Immediate early gene expression in the visual cortex of normal and dark reared cats: differences between fos and
George D Mower1, Irina V Kaplan
1Department of Anatomical Sciences and Neurobiology, University of Louisville, School of Medicine, 500 South Preston Street, Louisville, KY 40202, USA. george.mower@louisville.edu
Brain Research. Molecular Brain Research
|October 26, 2002
Abstract:
Northern blotting indicated that the level of induced fos was higher in normal than dark reared cat visual cortex (VC) at 5 weeks of age, comparable at 10 weeks, and higher in dark reared than normal cat visual cortex at 20 weeks. Fos egr-1, induction was higher in dark reared visual cortex at all ages. Thus, dark rearing has similar effects on fos, but not egr-1, expression as it has on physiological neuronal plasticity during the VC critical period.