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Related Experiment Videos

Sex and acute stroke presentation.

Lise A Labiche1, Wenyaw Chan, Kamaldeen R Saldin

  • 1Stroke Program, University of Texas Medical School at Houston, USA.

Annals of Emergency Medicine
|October 26, 2002
PubMed
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Women experiencing acute stroke symptoms are more likely to report nontraditional signs than men. Recognizing these sex differences in stroke presentation can improve emergency care for women.

Area of Science:

  • Neurology
  • Emergency Medicine
  • Public Health

Background:

  • Acute stroke presentation in emergency departments (EDs) is critical for timely intervention.
  • Understanding sex-based differences in symptom reporting may impact diagnostic accuracy and treatment initiation.

Purpose of the Study:

  • To investigate potential sex differences in the way acute stroke symptoms are presented in an emergency department setting.

Main Methods:

  • Prospective observational study of 1,189 validated stroke cases in nonurban EDs.
  • Structured interviews with patients and accompanying individuals to identify presenting symptoms.
  • Physician classification of reported symptoms into 14 categories, blinded to patient sex.

Main Results:

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  • Nontraditional stroke symptoms were reported by 28% of women versus 19% of men (OR 1.62).
  • Women more frequently reported pain and altered consciousness; men more frequently reported imbalance and hemiparesis.
  • Women were more likely to present with nonneurologic symptoms, while men were more likely to present with gait abnormalities.

Conclusions:

  • A notable sex difference exists in the reporting of acute stroke symptoms.
  • Women with stroke more frequently present with nontraditional symptoms compared to men.
  • Identifying these sex-specific presentation patterns can enhance the rapid evaluation and management of female stroke patients.