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Published on: May 15, 2019
[Attenuation of chronic stress-induced hippocampal damages following physical exercise]
Qiang Ma1, Jing Wang, Hong-Tao Liu
1Institute of Health and Environmental Medicine, Academy of Military Medical Sciences, Tianjin, China. maqiangw@Hotmail.com
Abstract:
The long-term potentiation (LTP) in the hippocampal dentate gyrus and the plasma glucocorticoids level were observed in rats to study the effects of physical exercise on chronic stress-induced hippocampal damages. Eight-week spontaneous wheel running exercise could attenuate the suppression of LTP induced by 21-day restraint stress, and maintain the normal plasma glucocorticoids levels. It is suggested that long-term physical exercise may protect the hippocampus from stress-induced damages.
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