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Updated: May 16, 2026

Monitoring Protein Adsorption with Solid-state Nanopores
Published on: December 2, 2011
Observation and evaluation of proton diffusion in porous media by the pH-imaging microscope using a flat
Satoshi Nomura1, Yan-Gou Yang, Chihiro Inoue
1R&D Center, Horiba Ltd, Kisshoinmiyanohigashimachi, Kyoto, Japan. nomura-s@horiba.co.jp
Abstract:
The diffusion of protons in porous media was observed and evaluated using a pH-imaging microscope with a flat semiconductor. Small particles were packed on the sensing surface of the flat sensor, followed by the addition of a lactic acid droplet on the top of the packed particle layer. The pH distribution accompanied by the diffusion of lactic acid was visualized at the bottom of the layer using the flat sensor. The difference in the diffusion property was confirmed depending on the particle type. The effective diffusion coefficients of the lactic acid in some porous media were estimated by combining the experimental results and mathematical calculation.
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