Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Multifactorial diseases: asthma genetics point the way.

Kourosh R Ahmadi1, David B Goldstein

  • 1Twin Research and Genetic Epidemiology Unit, St.Thomas' Hospital, London, UK.

Current Biology : CB
|October 29, 2002
PubMed
Summary

Genetic variations in the ADAM33 gene are linked to asthma risk. This discovery offers hope for new asthma diagnostics and treatments for patients.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Precision Diagnosis in APOL1 Kidney Disease With the p.N264K M1 Protective Variant.

JAMA network open·2026
Same author

Patient-reported characteristics of pernicious anaemia: a first step to initiate James Lind Alliance Priority Setting Partnership driven research.

BMC primary care·2025
Same author

Cohort profile: the Maharashtra Anaemia Study 3 (MAS 3)-a maternal-child cohort study up to age 18 years in India.

BMJ open·2025
Same author

Addressing the Gaps in the Vitamin B12 Deficiency 2024 NICE Guidelines: Highlighting the Need for Better Recognition, Diagnosis, and Management of Pernicious Anaemia.

European journal of clinical nutrition·2025
Same author

The impact of TRPV4 pathogenic mutations on barrier integrity.

Human molecular genetics·2025
Same author

RNA methyltransferase SPOUT1/CENP-32 links mitotic spindle organization with the neurodevelopmental disorder SpADMiSS.

Nature communications·2025

Area of Science:

  • Genetics
  • Pulmonology
  • Molecular Biology

Background:

  • Asthma is a common respiratory condition with complex genetic underpinnings.
  • Identifying specific genetic risk factors is crucial for understanding disease mechanisms.

Purpose of the Study:

  • To investigate the role of ADAM33 gene variations in asthma susceptibility.
  • To explore the potential of genetic factors in asthma diagnostics and therapeutics.

Main Methods:

  • Genetic association studies were employed.
  • Analysis focused on variations within the ADAM33 gene.

Main Results:

  • A significant association was found between ADAM33 gene variations and increased asthma risk.
  • This highlights ADAM33 as a key genetic contributor to asthma.

Conclusions:

  • ADAM33 gene variation is an important risk factor for asthma.
  • Findings encourage further genetic research into common diseases and may lead to novel diagnostic and treatment strategies.

Related Experiment Videos