Related Experiment Video
Updated: Sep 28, 2026

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
Published on: March 14, 2017
Psychosocial problems in children with thalassemia and their siblings
Orawan Louthrenoo1, Somjai Sittipreechacharn, Pattra Thanarattanakorn
1Department of Pediatrics, Faculty of Medicine, Chiang Mai University, Thailand.
Insights
Children with beta-thalassemia experience significantly more psychosocial problems than healthy children. Early psychosocial interventions are crucial for managing these challenges and preventing psychiatric disorders in affected children.
Area of Science:
- Pediatric Psychology
- Hematology
- Child Psychiatry
Background:
- Beta-thalassemia presents significant health challenges for children and families.
- Chronic illness in childhood can impact psychosocial well-being.
- Understanding these impacts is vital for comprehensive care.
Purpose of the Study:
- To assess psychosocial problems in children with beta-thalassemia.
- To compare these problems with those in siblings and healthy controls.
- To identify the need for targeted psychosocial interventions.
Main Methods:
- Utilized semi-structured interviews and the Pediatric Symptom Checklist (PSC).
- Included 82 children with thalassemia, 20 siblings, and 50 healthy controls.
- Demographically controlled for family and child characteristics.
Main Results:
- Children with beta-thalassemia showed significantly higher rates of psychosocial problems (28.05%) compared to controls (4%).
- No significant difference in psychosocial problems was found between siblings and controls.
- Mean PSC scores were markedly higher in children with thalassemia.
Conclusions:
- Children with beta-thalassemia face an elevated risk of psychosocial difficulties.
- Psychosocial interventions are recommended to mitigate risks and prevent psychiatric disorders.
- Further research into tailored support for this population is warranted.
Abstract:
Beta-thalassemia is a chronic illness causing serious symptoms to children and a burden to families. The purpose of this study was to evaluate psychosocial problems in children with thalassemia and their siblings by using a semi-structured interview and the Pediatric Symptom Checklist (PSC). The study sample included 82 children with thalassemia, 20 siblings, and 50 control children without a chronic illness. With children and families demographically controlled, psychosocial problems were significantly more common in children with thalassemia than in those without chronic illness, 28.05 per cent vs 4 per cent (p=0.001), but there was no difference between siblings and the controls, 5 per cent vs 4 per cent (p=0.64). The mean PSC score in children with thalassemia was higher than that in the sibling and control group (18.34 vs 10.95 and 10.28, respectively; p<0.001). These findings suggest an increased risk of psychosocial problems in children with thalassemia that psychosocial intervention may be required to prevent major psychiatric disorders.
Related Concept Videos
Relationship with Other Adult Family Members and Siblings
Socioemotional Development during Infancy
Primary Temperament Types
Stella Chess...
Psychological and Sociocultural Causes of Schizophrenia
Erikson's Theory on Socioemotional Development during Childhood
The first four of Erikson's eight psychosocial stages...
Socioemotional Experience and Gender Development
Adler's Individual Psychology