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Percutaneous renal biopsy in children
Achra Sumboonnanonda1, Krissada Srajai, Arun Vongjirad
1Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Summary
Pediatric renal biopsies are safe and beneficial, with most cases yielding diagnostic information. Hematuria was the most common complication, but serious adverse events were rare, supporting the procedure
Area of Science:
- Pediatric Nephrology
- Interventional Procedures
- Diagnostic Medicine
Background:
- Percutaneous renal biopsy is a crucial diagnostic tool in pediatric nephrology.
- Evaluating the safety and efficacy of this procedure in children is essential for clinical practice.
- Previous studies have highlighted potential complications and diagnostic yield, necessitating further investigation.
Purpose of the Study:
- To evaluate the safety and clinical benefit of percutaneous renal biopsies in pediatric patients.
- To identify the most common indications for renal biopsy in this age group.
- To assess the incidence and types of complications associated with the procedure.
Main Methods:
- A retrospective review of percutaneous renal biopsies performed between January 2000 and March 2001.
- Inclusion of 85 pediatric patients (90 episodes) with detailed analysis of patient demographics, indications, and procedural details.
- Ultrasound guidance and a modified 13 G Vim-Silverman needle were utilized.
Main Results:
- Nephrotic syndrome and systemic lupus erythematosus were the primary indications for biopsy.
- The most frequent complication was hematuria (74.4%), with gross hematuria in 23.3%.
- A high Clinical Benefit Score (2) was achieved in 89.4% of cases, indicating significant diagnostic and therapeutic value.
Conclusions:
- Percutaneous renal biopsy in pediatric patients is a safe procedure with a high clinical benefit.
- The current practice demonstrates a favorable risk-benefit profile for diagnosing pediatric kidney diseases.
- Further research into ultrasound-guided techniques and newer biopsy devices may further reduce complication rates.