Emergency coronary artery bypass surgery in the contemporary percutaneous coronary intervention era
Niranjan Seshadri1, Patrick L Whitlow, Naveen Acharya
1Department of Cardiology, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.
Insights
Emergency coronary artery bypass surgery (CABG) after percutaneous coronary interventions (PCI) is decreasing but remains high-risk. Female sex and lesion severity predict need, while prior bypass and stents reduce it.
Area of Science:
- Cardiology
- Interventional Cardiology
- Cardiac Surgery
Background:
- Percutaneous coronary interventions (PCIs) have advanced, reducing complications.
- Emergency coronary artery bypass surgery (CABG) following PCI still carries significant risks.
- The study examines emergency CABG after PCI over a decade.
Purpose of the Study:
- To determine the prevalence of emergency CABG after PCI.
- To identify indications, predictors, and complications of emergency CABG.
- To analyze trends in emergency CABG over a ten-year period.
Main Methods:
- Retrospective review of 18,593 PCIs performed between 1992 and 2000.
- Analysis of indications for emergency CABG, including dissection, perforation, and acute closure.
- Statistical analysis to identify predictors and complications.
Main Results:
- Emergency CABG was required in 0.61% of PCIs.
- Indications included extensive dissection (54%), perforation/tamponade (20%), and acute closure (20%).
- Prevalence decreased from 1.5% to 0.14% (P<0.001). Predictors: higher ACC/AHA score, female sex. Protective factors: prior bypass, stent use.
Conclusions:
- The need for emergency CABG post-PCI has significantly declined.
- Female sex and higher lesion severity (ACC/AHA score) are risk factors.
- Despite the decrease, emergency CABG remains associated with high morbidity and mortality.
Background:
Since the advent of percutaneous coronary interventions (PCIs), technological advances, adjunctive pharmacotherapy, and increasing operator experience have contributed to lowering the occurrence of major complications. However, emergency coronary artery bypass surgery (CABG) for failed PCI is still associated with important morbidity and mortality, even in the era of coronary stenting. We sought to determine the prevalence, indications, predictors, and complications of emergency CABG after PCI in the past decade.
Methods And Results:
We reviewed 18 593 PCIs performed from 1992 through 2000. There was a need for emergency CABG in 113 (0.61%) cases. The major indications were extensive dissection (n=61, 54%), perforation/tamponade (n=23, 20%), and recurrent acute closure (n=23, 20%). Prevalence of emergency CABG decreased from 1.5% of PCIs in 1992 to 0.14% in 2000 (P<0.001). Independent predictors of the need for emergency CABG included the worst ACC/AHA scoring of the intervened lesion (P<0.001) and female sex (P= 0.028), whereas history of prior bypass surgery and use of stents resulted in a decreased need for emergency CABG (P<0.001 for both). In patients undergoing emergency CABG, there were 17 (15%) in-hospital deaths, 14 (12%) perioperative Q-wave myocardial infarctions, and 6 (5%) cerebrovascular accidents.
Conclusions:
The need for emergency CABG has considerably decreased over time. Risk factors include female sex and a higher ACC/AHA score of the intervened lesion. However, morbidity and mortality of emergency CABG remain high even in the new millennium.
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