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Paget's disease of bone: presentation, extent and response to bisphosphonates
L M Wang1, M L Au-Yeong, M J McKenna
1St. Michael's Hospital, Dún Laoghaire, Co. Dublin.
Irish Medical Journal
|October 31, 2002
Abstract:
According to a radiograph survey in 1982, Paget's disease of bone is common in Ireland but, to date, there have been no clinical reports. In a survey of 24 patients with Paget's disease of bone, we found monostotic disease in 8 and polyostotic disease in 16. Complications were common including deformity (21%), fracture (17%) and deafness (8%). Bisphosphonate therapy induced a remission in 22 patients.