Related Experiment Video
Updated: Aug 9, 2026

Isolation of Cells with Morphological and Spatial Information from Oral Submucous Fibrosis Samples by Laser Capture Microdissection
Published on: August 11, 2023
Ameloblastomatoid, central odontogenic fibroma: an epithelium-rich variant
Fumio Ide1, Hideaki Sakashita, Kaoru Kusama
1Department of Oral Pathology, Meikai University School of Dentistry, Saitama, Japan.
Abstract:
Two cases are presented of a central odontogenic fibroma (OF) in the mandible of a middle-aged female, which posed considerable difficulty in microscopic diagnosis. These well-demarcated but non-encapsulated intraosseous tumors had hybrid features of both OF and ameloblastoma. Their clinical findings are more in keeping with the putative OF rather than ameloblastoma. The present lesions alert pathologists to this unusual type of central OF in order to avoid misdiagnosis.
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