Is pulpitis painful?
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Updated: Sep 28, 2026

Establishment of a Murine Pulp Exposure Model with a Novel Mouth-Gag for Pulpitis Research
Published on: October 27, 2023
1Division of Endodontics, School of Dentistry, University of Michigan, Ann Arbor, MI, USA.
Aim:
To determine whether inflamed dental pulps progress to necrosis without pain.
Methodology:
Records of 2,202 maxillary anterior teeth endodontically treated at the University of Michigan were collected. Records of teeth presenting with periapical radiolucencies but no response to vitality tests were examined further to determine, from the history, whether the patient had experienced pain or no pain from the involved tooth.
Results:
Approximately 40% of the teeth included gave no history of spontaneous or prolonged pain to a thermal stimulus. No statistically significant differences in the incidence of 'painless pulpitis' were related to either gender or tooth type. Patients aged >53 years experienced 'painless pulpitis' more often than patients <33 years.
Conclusions:
Many teeth appear to progress to pulpal necrosis without the patient experiencing pain attributable to the pulp.
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