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Updated: Sep 28, 2026

System for Focal, Closed-System Central Nervous System Injury
Published on: November 29, 2024
[Infections after missile head injury. Experience during the Lebanese civilian war]
G Nohra1, J Maarrawi, E Samaha
1Service de Neurochirurgie, Hôtel-Dieu de France, Beyrouth, Liban, France. neurochhdf@intracom.net.lb
Objective:
Establish the risk factors for infection following missile head injuries (MHI).
Methods:
Between 1975 and 1990, 500 cases of MHI were admitted, with only 272 responding to inclusion criteria. After initial evaluation including CT scan for 177 patients, all underwent craniectomy with debridement and duroplasty. A retrospective study was undertaken in order to identify the risk factors that increase the infection rate.
Results:
The global infection rate was 11.39%. Among the studied factors, those increasing the infection rate were: coma on admission (17.6% vs 7.6%), penetrating wounds (12.93% vs 7% for tangential wounds), intracerebral trajectory length over 6 cm (18.42% vs 6.32%), air sinuses effraction (25.8% vs 9.54%), a surgical delay over 72 hours (41.6% vs 10.6%), inadequate duroplasty (28% vs 7.33%), cerebrospinal fluid (CSF) fistulae (58.62% vs 5.76%). The presence of postoperative bone fragments did not increase the infection rate (11.4% vs 11.2%).
Discussion And Conclusion:
Adequate duroplasty and aggressive treatment of CSF fistulae decrease the infection rate. There is no need to reoperate on residual bone fragments after adequate debridment. A delay of 24 to 48 hours should be considered, to facilitate the procedure without increasing the infection risk.
Insights
Infection risk after missile head injuries (MHI) is reduced by adequate duroplasty and CSF fistula treatment. Delaying surgery 24-48 hours may be beneficial without increasing infection risk.
Area of Science:
- Neurosurgery
- Infectious Disease Epidemiology
- Trauma Surgery
Context:
- Missile head injuries (MHI) pose significant risks of post-operative infection.
- Understanding risk factors is crucial for optimizing patient outcomes.
- This study retrospectively analyzed MHI cases to identify infection predictors.
Purpose:
- To establish the key risk factors associated with infection following missile head injuries.
- To identify surgical and injury-related factors influencing post-MHI infection rates.
- To inform clinical practice for reducing infection complications.
Summary:
- The global infection rate in MHI cases was 11.39%.
- Risk factors for infection include coma on admission, penetrating wounds, long intracerebral trajectory, air sinus involvement, delayed surgery (>72 hours), inadequate duroplasty, and CSF fistulae.
- Postoperative bone fragments did not significantly increase infection risk.
Impact:
- Adequate duroplasty and aggressive CSF fistula management are vital for decreasing infection rates.
- Reoperation for residual bone fragments is unnecessary after thorough debridement.
- A surgical delay of 24-48 hours may be considered to mitigate infection risk.
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