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Cytogenetics and molecular genetics of ovarian cancer
1University of Rochester, School of Medicine, New York, USA. nancy_wang@urmc.rochester.edu
American Journal of Medical Genetics
|October 31, 2002
Abstract:
Genetic alterations identified in human ovarian tumors by conventional banding, fluorescence in situ hybridization, comparative genomic hybridization, chromosome microdissection, loss of heterozygosity, chromosome microcell-mediated chromosome transfer, and microarray gene expression analysis are summarized and correlated. The significance of these findings with respect to pathologic classification and clinical application are discussed.