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[Pulse pressure and coronary disease].

N Danchin1

  • 1Service de cardiologie, hôpital européen Georges-Pompidou, 20 rue Leblanc, 75015 Paris. Nicolas.danchin@egp.ap-hop-paris.fr

Archives Des Maladies Du Coeur Et Des Vaisseaux
|November 1, 2002
PubMed
Summary

Pulse pressure, the difference between systolic and diastolic blood pressure, is increasingly recognized as a significant predictor of cardiovascular events. Elevated pulse pressure is linked to coronary artery disease, myocardial infarction, and restenosis after procedures.

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Area of Science:

  • Cardiology
  • Vascular Physiology

Context:

  • Pulse pressure (PP) has emerged as a critical clinical parameter over the last decade.
  • Observational studies link elevated PP to increased risk of coronary events, particularly in the elderly.
  • High PP correlates with angiographically confirmed coronary artery disease and elevated C-reactive protein levels.

Purpose:

  • To synthesize the growing evidence on the prognostic value of pulse pressure in cardiovascular disease.
  • To highlight the association between pulse pressure and various adverse cardiovascular outcomes.

Summary:

  • Pulse pressure is a significant predictor of late coronary events in the general population.
  • In patients with established coronary artery disease, PP is a prognostic factor post-myocardial infarction and revascularization.
  • Studies indicate a correlation between high PP and restenosis after percutaneous transluminal coronary angioplasty.

Impact:

  • Pulse pressure measurement offers a valuable, non-invasive tool for risk stratification in cardiovascular patients.
  • Understanding the role of PP can refine clinical management strategies for coronary artery disease.
  • Further research into the mechanisms linking PP to cardiovascular events is warranted.

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