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Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

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Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
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Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption01:22

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption

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As individuals age, their body's physiology evolves, affecting drug pharmacokinetics. The most apparent changes occur in the gastrointestinal tract, where an increase in gastric pH, a delay in gastric emptying, and a reduction in gastrointestinal motility are observed. Remarkably, these changes do not substantially modify the absorption of orally administered drugs, particularly those absorbed via passive diffusion.Transdermal drug delivery emerges as a highly viable method for older adults due...
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Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution01:00

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution

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Drug distribution in the human body is influenced by several factors, including plasma protein concentration, body composition, blood flow, tissue-protein concentration, and tissue fluid pH. Among these, changes in plasma protein concentration and body composition due to aging significantly affect how drugs are distributed within the body. Specifically, aging is associated with a decrease in albumin levels by about 10% and an increase in α1-acid glycoprotein levels. These alterations are...
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Pharmacodynamics in Geriatric Patients: Effects of Age01:27

Pharmacodynamics in Geriatric Patients: Effects of Age

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Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
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Current Trends in Nursing I01:28

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Current trends in nursing include:
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The Effect of Aging on Tissues01:19

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Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
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Related Experiment Video

Updated: Jan 19, 2026

A Computerized Functional Skills Assessment and Training Program Targeting Technology Based Everyday Functional Skills
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Challenges of an aging population.

M Gordon1

  • 1Baycrest Centre for Geriatric Care, 3560 Bathurst St., North York ON M6A 2E1, Canada. m.gordon@Baycrest.org

Annals (Royal College of Physicians and Surgeons of Canada)
|November 1, 2002
PubMed
Summary

The aging population requires increased healthcare and social support. Physicians need training on ethical elder care to ensure quality of life for seniors facing conditions like dementia and Parkinson's disease.

Area of Science:

  • Gerontology
  • Public Health
  • Medical Ethics

Background:

  • The global population is aging, increasing demand for elder care resources.
  • Advances in medicine extend life, but also increase prevalence of age-related conditions.

Purpose of the Study:

  • To highlight the growing need for healthcare and social support for the elderly.
  • To emphasize the importance of ethical considerations in geriatric care.

Main Methods:

  • Literature review on aging trends and medical advancements.
  • Analysis of clinical and ethical challenges in elder care.

Main Results:

  • Increased longevity presents opportunities for fulfilling lives.
  • Medical progress addresses conditions like dementia, stroke, Parkinson's, depression, and osteoporosis.
Keywords:
Health Care and Public Health

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Conclusions:

  • Healthcare and social service professionals must be prepared for the complexities of aging.
  • Medical education needs to integrate comprehensive training on aging issues for physicians.