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Percutaneous microwave coagulation therapy for lung cancer
Weijian Feng1, Wei Liu, Caiying Li
1Department of Medical Oncology, Fourth Hospital, Hebei Medical University, Shijiazhuang 050011, China.
Zhonghua Zhong Liu Za Zhi [Chinese Journal of Oncology]
|November 1, 2002
Summary
Percutaneous microwave coagulation therapy effectively treats lung cancer, with significant tumor reduction and no observed side-effects. This minimally invasive procedure shows promising results for both primary and metastatic lung cancer patients.
Area of Science:
- Oncology
- Minimally Invasive Procedures
- Medical Imaging
Background:
- Lung cancer remains a leading cause of cancer-related mortality worldwide.
- Effective and minimally invasive treatment options are crucial for improving patient outcomes.
- Percutaneous therapies offer a potential alternative to traditional treatments.
Purpose of the Study:
- To assess the clinical efficacy of percutaneous microwave coagulation therapy (PMCT) for lung cancer.
- To document CT imaging changes following PMCT.
- To evaluate the safety and side-effect profile of PMCT in lung cancer patients.
Main Methods:
- CT-guided percutaneous microwave coagulation therapy was administered to 20 peripheral lung cancer patients (8 primary, 12 metastatic).
- A 65W, 2450 MHz microwave was delivered via a needle monopole antenna over 60 seconds per lesion.
- A total of 28 lesions were treated, with follow-up assessments including CT imaging and clinical evaluation.
Main Results:
- After a median follow-up of 24 months, 16 patients survived.
- Significant tumor size reduction was observed in all patients; 13 lesions showed >50% diminution, and 3 disappeared completely.
- Complete tumor necrosis was confirmed by biopsy, with an overall response rate of 57.1% and no reported side-effects or complications.
Conclusions:
- Percutaneous microwave coagulation therapy is a safe and effective treatment for lung cancer.
- PMCT demonstrates significant therapeutic effects with minimal patient trauma.
- This technique represents a promising new option for managing lung cancer, particularly for peripheral lesions.