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Updated: Sep 28, 2026

Analysis of LINE-1 Retrotransposition at the Single Nucleus Level
11:52

Analysis of LINE-1 Retrotransposition at the Single Nucleus Level

Published on: April 23, 2016

A novel endogenous retrovirus-related element in the human genome resembles a DNA transposon: evidence for an

Jennifer F Hughes1, John M Coffin

  • 1Department of Molecular Biology and Microbiology and Program in Genetics, Tufts University School of Medicine, 136 Harrison Avenue, Boston, Massachusetts, 02111, USA.

Genomics
|November 1, 2002
PubMed

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Non-LTR Retrotransposons

As the name suggests, non-LTR retrotransposons lack the long terminal repeats characteristic of the LTR retrotransposons. Additionally, both LTR and non-LTR retrotransposons use distinct mechanisms of mobilization. Non-LTR retrotransposons are further divided into two classes - Long interspersed nuclear elements (LINEs) and short interspersed nuclear elements (SINEs), both of which occur abundantly in most mammals, including humans. Some of the active non-LTR retrotransposons in humans are L1...
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