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Chemical and anti-platelet constituents from Formosan Zanthoxylum simulans
Ya-Ping Yang1, Ming-Jen Cheng, Che-Ming Teng
1Graduate Institute of Natural Products, Kaohsiung Medical University, Kaohsiung, Republic of, Taiwan, China.
Phytochemistry
|November 1, 2002
Abstract:
A pyrrole alkaloid, pyrrolezanthine [5-hydroxymethyl-1-[2-(4-hydroxyphenyl)-ethyl]-1H-pyrrole-2-carbaldehyde]; a lignan, (-)-simulanol [4- [3-hydroxymethyl-5-((E)-3-hydroxypropenyl)-7-methoxy-2,3-dihydrobenzofuran-2-yl]-2,6-dimethoxy-phenol] and a monocyclic gamma-pyrone, zanthopyranone [3,5-dimethoxy-2-methyl-pyran-4-one], together with 28 known compounds were isolated from the stem wood of Formosan Zanthoxylum simulans. Their structures were determined through spectral analyses. Among the isolates, 11 compounds showed anti-platelet aggregation activity in vitro.