Related Experiment Video
Updated: Aug 14, 2026

Establishment of Cancer Stem Cell Cultures from Human Conventional Osteosarcoma
Published on: October 14, 2016
Primary skeletal neoplasms: osteosarcoma and ewing sarcoma
1Department of Diagnostic Imaging, St. Jude Children's Research Hospital, 325 North Lauderdale, Memphis, TN 38105, USA. fred.hoffer@stjude.org
Abstract:
The care for children and adolescents with malignant bone tumors such as osteosarcoma and Ewing sarcoma will be improved by the magnetic resonance imager that can recognize the tumor early in its course and can stage it correctly for proper chemotherapy and local control. This can be accomplished by attention to the proper magnetic resonance imaging technique, recognition of the magnetic resonance appearance, and knowledge of the prognostic factors at diagnosis. Determination of response on follow-up static and dynamic contrast-enhanced magnetic resonance imaging and knowledge of optimal methods to determine recurrent tumor will improve the outcome for these children.
Related Concept Videos
Metastasis
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
Cancer Therapies
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
Rous Sarcoma Virus (RSV) and Cancer
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...
Rous Sarcoma Virus (RSV) and Cancer
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...
Bone Cells and Tissue
Osteoblasts and Osteocytes
The osteoblast is the bone cell responsible for forming new bone tissue. It is found in the growing portions of bone, including the periosteum and...
Bone Formation by Endochondral Ossification

