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Related Experiment Videos

Conservative management in neurogenic bladder dysfunction.

Ahmet R Aslan1, Barry A Kogan

  • 1Division of Urology, Albany Medical College, New York 12208, USA.

Current Opinion in Urology
|November 1, 2002
PubMed
Summary

New therapies for spina bifida are reducing the need for urinary diversion surgery. Advances in medications and administration methods offer alternatives to bladder augmentation, improving patient outcomes.

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Area of Science:

  • Pediatric Urology
  • Neurogenic Bladder Management
  • Spina Bifida Therapeutics

Background:

  • Historically, ileal conduit urinary diversion was standard for pediatric spina bifida.
  • Clean intermittent catheterization (CIC) has revolutionized neurogenic bladder management.
  • Recent pharmaceutical advancements have significantly reduced the need for surgical interventions.

Purpose of the Study:

  • To review current and emerging therapeutic modalities for managing neurogenic bladder in spina bifida.
  • To highlight strategies aimed at avoiding urinary diversion or bladder augmentation.
  • To present the latest data on conservative management of bladder dysfunction.

Main Methods:

  • Review of recent literature on pharmacotherapy and minimally invasive treatments.

Related Experiment Videos

  • Analysis of new drug generations and administration techniques.
  • Evaluation of investigational therapies like neuromodulation and biofeedback.

    • Main Results:

    • New anticholinergic drugs (e.g., tolterodine) and novel administration routes (extended-release, intravesical) are available.
    • Intravesical treatments like botulinum-A toxin and resiniferatoxin offer alternatives for refractory cases.
    • Electrical stimulation and sacral nerve stimulation show promise but require further development.

    Conclusions:

    • Conservative management strategies are increasingly effective in preventing the need for bladder augmentation.
    • A range of alternatives to surgical intervention are now available for pediatric spina bifida patients.
    • Ongoing research is focused on developing even more effective non-surgical treatments.