Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Peripheral ameloblastic fibrosarcoma].

Jean-Philippe Dufau1, Patricia Paume, Raoulin Soulard

  • 1Service d'Anatomie Pathologique, CHRU de Lille, France.

Annales De Pathologie
|November 1, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Type I interferon-dependent and -independent signaling underlie autoantibody production in a murine lupus model.

Journal of translational autoimmunity·2026
Same author

Human LY9 governs CD4<sup>+</sup> T cell IFN-γ immunity to <i>Mycobacterium tuberculosis</i>.

Science immunology·2025
Same author

Impaired development of memory B cells and antibody responses in humans and mice deficient in PD-1 signaling.

Immunity·2024
Same author

Gene: environment interactions in immune and inflammatory responses to severe acute respiratory syndrome coronavirus 2 infection.

Current opinion in immunology·2024
Same author

In vivo CRISPR screens reveal SCAF1 and USP15 as drivers of pancreatic cancer.

Nature communications·2024
Same author

Human inherited CCR2 deficiency underlies progressive polycystic lung disease.

Cell·2024

This study reports the first case of peripheral ameloblastic fibrosarcoma (PAFS) in an elderly patient with a history of recurrent peripheral ameloblastoma. The findings highlight the rarity and unique presentation of this rare odontogenic tumor.

Area of Science:

  • Oral Pathology
  • Oncology
  • Surgical Pathology

Background:

  • Peripheral ameloblastic fibrosarcoma (PAFS) is a rare odontogenic tumor.
  • Odontogenic tumors typically occur centrally within bone, but peripheral variants can arise in soft tissues.

Observation:

  • A case of PAFS is presented in an 89-year-old male with a history of recurrent peripheral ameloblastoma.
  • Histologically, the tumor showed features of both sarcomatous proliferation and benign ameloblastomatous areas.
  • This represents the first reported case of PAFS in the literature, likely reflecting the rarity of its central counterpart.

Findings:

  • The differential diagnosis includes low-grade spindle ameloblastic carcinoma and collision tumors.
  • The tumor's occurrence in an elderly patient is atypical, as PAFS usually affects adolescents or young adults.

Related Experiment Videos

  • The close proximity to a recurrent peripheral ameloblastoma is a notable feature.

    • Implications:

    • Peripheral odontogenic tumors may require long-term follow-up due to potential recurrence.
    • Aggressive initial surgical management might be considered for peripheral odontogenic tumors.
    • This case expands the understanding of the clinicopathological spectrum of rare odontogenic tumors.