Current management options in Behçet's disease

Behçet's disease (BD) is a multi-system inflammatory disorder, which causes recurrent oral and genital ulceration, intraocular inflammation and skin lesions. Less commonly, locomotor, vascular, neurological and gastro-intestinal manifestations may occur. The pathophysiology of Behçet's disease is not well understood, but may involve a generalised vascular dysfunction. Although rare in Western Europe, BD can cause significant morbidity and mortality to affected individuals. In this article, we review the clinical features and discuss current management options.