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Related Experiment Videos

Plexiform neurofibroma during and after pregnancy.

M Isikoglu1, R Has, D Korkmaz

  • 1Department of Obstetrics and Gynecology, Istanbul Medical Faculty, Istanbul University, 9-10 Kisim B-18 Daire 52 Atakoy/Istanbul, 34750 Turkey.

Archives of Gynecology and Obstetrics
|November 1, 2002
PubMed
Summary

Pregnancy can cause plexiform neurofibromas, a rare genetic condition, to grow. This thigh neurofibroma case study shows it shrank postpartum.

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Area of Science:

  • Genetics and Obstetrics
  • Dermatology and Oncology

Background:

  • Neurofibromatosis is a genetic disorder impacting multiple organ systems with diverse clinical presentations.
  • Pregnancy complicates neurofibromatosis in 1:2434 to 1:18,500 deliveries.
  • Plexiform neurofibromas are uncommon subcutaneous growths that can cause deformities.

Observation:

  • A patient presented with a giant plexiform neurofibroma on the thigh.
  • The neurofibroma significantly increased in size during pregnancy.

Findings:

  • The giant thigh neurofibroma demonstrated growth during gestation.
  • Postpartum, the neurofibroma showed a slight reduction in size.

Implications:

  • This case highlights the impact of pregnancy on neurofibroma growth.

Related Experiment Videos

  • Understanding these changes is crucial for managing neurofibromatosis during pregnancy and postpartum.