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Simvastatin-nelfinavir interaction implicated in rhabdomyolysis and death

C Bradley Hare¹, Mai P Vu, Carl Grunfeld

¹Division of Infectious Diseases, University of California, San Francisco, California 94110, USA. chare@php.ucsf.edu

Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America

|November 1, 2002

Abstract:

We report the first death associated with rhabdomyolysis in a patient treated with a statin and a protease inhibitor, which produced a significant drug-drug interaction.

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