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The relationship between myelodysplastic syndromes and autoimmune disorders
Shi Zhao1, Hong Mao, Hongxiang Wang
1Department of Hematology, The Second Hospital of Wuhan, Wuhan 430014, China.
Zhonghua Xue Ye Xue Za Zhi = Zhonghua Xueyexue Zazhi
|November 2, 2002
Abstract
Objective:
To explore the relationship between the myelodysplastic syndromes (MDS) and autoimmune disorders (AID).
Methods:
The clinical data of 117 MDS patients were reviewed.
Results:
Nineteen (16.2%) of 117 MDS patients had AIDs. The commonest AID associated with MDS was rheumatoid arthritis (31.6%) and ulcerative colitis (26.3%). Compared with that in MDS patients without autoimmune disorders, the leukemic transformation rate was not increased in the MDS/AID but the median survival time was shorter in MDS/AID patients.
Conclusion:
MDS patients associated with autoimmune disorders may be an unfavorable factor for their prognosis.