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Related Experiment Videos

Components for integrated poly(dimethylsiloxane) microfluidic systems.

Jessamine M K Ng1, Irina Gitlin, Abraham D Stroock

  • 1Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, MA 02138, USA.

Electrophoresis
|November 2, 2002
PubMed
Summary
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This review details the design and fabrication of microfluidic systems using poly(dimethylsiloxane) (PDMS). PDMS offers advantages like elasticity and optical transparency, simplifying microfluidic device creation.

Area of Science:

  • Materials Science
  • Microfluidics Engineering

Background:

  • Poly(dimethylsiloxane) (PDMS) is a versatile soft polymer.
  • PDMS exhibits favorable properties including elasticity, optical transparency, and tunable surface chemistry.
  • Soft lithography is a key technique for fabricating microfluidic devices.

Purpose of the Study:

  • To review the design and fabrication of microfluidic systems in PDMS.
  • To highlight the advantages of PDMS for microfluidic applications.
  • To describe various integrated components for PDMS-based microfluidics.

Main Methods:

  • Fabrication of microfluidic systems using soft lithography.
  • Integration of passive and active components within PDMS devices.
  • Design of single and multilayer microfluidic architectures.

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Main Results:

  • PDMS enables straightforward fabrication of microfluidic systems.
  • PDMS offers convenient integration and user interfacing compared to hard materials.
  • Detailed descriptions of components like mixers, valves, and filters are provided.

Conclusions:

  • PDMS is an advantageous material for microfluidic system fabrication.
  • The described methods facilitate the creation of complex and functional microfluidic devices.
  • The review provides a comprehensive overview of PDMS microfluidics and its components.