Related Experiment Videos
Increase of separation resolution through field enhancement in microchips
Matthew B Kerby1, Ring-Ling Chien
1Caliper Technologies Corp., 605 Fairchild Drive, Mountain View, CA 94043, USA.
Electrophoresis
|November 2, 2002
Abstract:
An enhanced ability to separate charged species from neutral compounds in a microfluidic chip is demonstrated using a chip design with low-resistance electrode channels operating with a multiport pressure/voltage controller. A factor of 2.7 improvement in resolution was obtained from chips made using identical mask designs but different etch depth protocols. Greater separation power allows one to cover a wider dynamic range for compounds with different electrophoretic mobilities.