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Analytical aspects of mass spectrometry and proteomics
1Barnett Institute and Department of Chemistry, Northeastern University, 341 Mugar Hall, 360 Huntington Avenue, Boston, Massachusetts 02115, USA.
Current Opinion in Chemical Biology
|November 5, 2002
Abstract:
Mass spectrometry plays an essential role in proteomics analysis and research. In recent years, it has been increasingly recognized that a key to proteomics using mass spectrometry relies not only on the instrument itself, but also on the analytical strategies and front-end sample-handling techniques. The advances of separations and mass spectrometry are having an increasing impact on the discovery of disease biomarkers and the understanding of cellular processes.