Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Brucellosis in Central America.

Edgardo Moreno1

  • 1Tropical Disease Research Program, Veterinary School, National University, Apartado 304-3000, Heredia, Costa Rica. emoreno@ns.medvet.una.ac.cr

Veterinary Microbiology
|November 5, 2002
PubMed
Summary

Brucellosis remains a significant threat to animal and human health in Central America. Unrestricted adult vaccination with S19 offers a viable strategy to control brucellosis where new vaccines are unaffordable.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Pathogenicity of <i>Brucella</i> sp. ST27 <i>Kogia sima</i> Isolates in Murine and Cell Models.

Tropical medicine and infectious disease·2026
Same author

Author Correction: Brucella abortus impairs T lymphocyte responsiveness by mobilizing IL-1RA-secreting omental neutrophils.

Nature communications·2025
Same author

Brucella abortus impairs T lymphocyte responsiveness by mobilizing IL-1RA-secreting omental neutrophils.

Nature communications·2025
Same author

Reactivation of hidden-latent <i>Brucella</i> infection after doxycycline and streptomycin treatment in mice.

Antimicrobial agents and chemotherapy·2025
Same author

A sensor histidine kinase from a plant-endosymbiont bacterium restores the virulence of a mammalian intracellular pathogen.

Microbial pathogenesis·2023
Same author

The <i>Brucella abortus</i> two-component system response regulator BvrR binds to three DNA regulatory boxes in the upstream region of <i>omp25</i>.

Frontiers in microbiology·2023

Area of Science:

  • Veterinary Medicine
  • Zoonotic Diseases
  • Epidemiology

Context:

  • Brucellosis affects domestic animals and humans across Central America.
  • Bovine brucellosis (Brucella abortus) and swine brucellosis (Brucella suis) are endemic in all Central American countries.
  • Ovine and caprine brucellosis (Brucella melitensis) are present in Guatemala.

Purpose:

  • To evaluate the effectiveness of current brucellosis control programs in Central America.
  • To propose an alternative vaccination strategy for brucellosis in a resource-limited region.

Summary:

  • Bovine brucellosis prevalence ranges from 4-8%, particularly in dairy herds, causing an estimated annual loss of 25 million US dollars.
  • Existing control programs utilizing calf vaccination and reactor removal have shown limited success.
  • Unrestricted adult vaccination via the conjunctival route with the S19 vaccine is recommended as a cost-effective alternative.

Impact:

  • The proposed vaccination strategy aims to reduce bacterial prevalence and density, enabling future serological identification and elimination of infected animals.
  • This approach is expected to improve brucellosis control in Central America, mitigating economic losses and protecting public health.

Related Experiment Videos