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The genome of Brucella melitensis
Vito G DelVecchio1, Vinayak Kapatral, Philip Elzer
1Institute of Molecular Biology and Medicine, University of Scranton, Scranton, PA 18510, USA. vimbm@aol.com
Abstract:
The genome of Brucella melitensis strain 16M was sequenced and contained 3,294,931 bp distributed over two circular chromosomes. Chromosome I was composed of 2,117,144 bp and chromosome II has 1,177,787 bp. A total of 3,198 ORFs were predicted. The origins of replication of the chromosomes are similar to each other and to those of other alpha-proteobacteria. Housekeeping genes such as those that encode for DNA replication, protein synthesis, core metabolism, and cell-wall biosynthesis were found on both chromosomes. Genes encoding adhesins, invasins, and hemolysins were also identified.