Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Asthma.

A E Tattersfield1, A J Knox, J R Britton

  • 1Division of Respiratory Medicine, Clinical Sciences Building, City Hospital, Nottingham, UK. anne.tattersfield@nottingham.ac.uk

Lancet (London, England)
|November 5, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Slow growth rates of common carp Cyprinus carpio in English catch-and-release fisheries are related to high stock densities.

Journal of fish biology·2026
Same author

The North American fathead minnow Pimephales promelas in Europe: potential invader or a benign non-native fish?

Journal of fish biology·2025
Same author

Vicariance in a generalist fish parasite driven by climate and salinity tolerance of hosts.

Parasitology·2020
Same author

Is bigger really better? Towards improved models for testing how Atlantic salmon Salmo salar smolt size affects marine survival.

Journal of fish biology·2018
Same author

Fishes in a changing world: learning from the past to promote sustainability of fish populations.

Journal of fish biology·2018
Same author

Diagnostic and prognostic significance of systemic alkyl quinolones for P. aeruginosa in cystic fibrosis: A longitudinal study; response to comments.

Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society·2017
Same journal

Convergence of metabolic risk in obesity and normal BMI: does risk disappear?

Lancet (London, England)·2026
Same journal

Metabolic traits in obesity and normal BMI in industrialised countries: a multi-country analysis of national population-based studies.

Lancet (London, England)·2026
Same journal

Safety and efficacy of mRNA vaccines: a mechanistic and public health perspective.

Lancet (London, England)·2026
Same journal

The US Ebola response and the future of global health leadership.

Lancet (London, England)·2026
Same journal

Daniel Mason: a tale of change.

Lancet (London, England)·2026
Same journal

The 2026 Wakley-Wu Lien Teh Prize Essay: why medicine, and why stay?

Lancet (London, England)·2026
See all related articles

Asthma prevalence is rising due to environmental and genetic factors. Understanding these causes is key to developing better asthma prevention and treatments.

Area of Science:

  • Pulmonology
  • Genetics
  • Environmental Health

Background:

  • Asthma is a prevalent chronic respiratory disease, particularly in affluent societies, with increasing incidence.
  • Environmental factors are strongly implicated in asthma's rising prevalence, though specific triggers remain unclear.
  • Genetic susceptibility also plays a significant role, with multiple genes likely contributing moderate effects.

Purpose of the Study:

  • To review the current understanding of asthma's etiology, focusing on environmental and genetic influences.
  • To describe the immunological and pathological characteristics of asthmatic airways.
  • To outline current therapeutic strategies and highlight the need for improved approaches.

Main Methods:

  • Review of existing epidemiological, genetic, and clinical studies on asthma.

Related Experiment Videos

  • Analysis of the inflammatory and remodeling processes in asthma.
  • Evaluation of current asthma treatment guidelines and emerging therapies.

    • Main Results:

    • Asthma's increasing prevalence underscores the importance of environmental factors.
    • Genetic predisposition involves multiple genes with moderate effects.
    • Airways in asthma exhibit inflammation and remodeling involving CD4+ helper cells, mast cells, and eosinophils.
    • Inhaled corticosteroids and long-acting beta agonists are primary treatments; leukotriene antagonists offer modest benefits.

    Conclusions:

    • A comprehensive understanding of asthma's underlying mechanisms, genetic predispositions, and environmental triggers is crucial.
    • Further research into these factors will drive the development of enhanced preventative strategies and novel therapeutic interventions for asthma.