Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

2',3'-Dehydrosalannol.

R Malathi1, S S Rajan, Geetha Gopalakrishnan

  • 1Department of Crystallography and Biophysics, University of Madras, Guindy Campus, Chennai 600 025, India.

Acta Crystallographica. Section C, Crystal Structure Communications
|November 5, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Starved synapses: Gut microbiome dysbiosis and its role in Alzheimer's glucose impairment.

International review of neurobiology·2026
Same author

Time Critical Medicine Sticker for Inpatients with Parkinson's Disease.

Irish medical journal·2026
Same author

Integrating AI-blockchain framework with Spider Monkey Federated Extreme Learning for enhanced healthcare data protection.

Scientific reports·2026
Same author

Quantum optimized hierarchical chunk encoding with robust embedding for perceptual integrity and compression tolerant visual data protection.

Scientific reports·2026
Same author

Hydroxyapatite derived from eggshell embedded on functionalized g-C<sub>3</sub>N<sub>4</sub> for synergistic extraction of U(VI) from aqueous solution.

Chemosphere·2024
Same author

Predictors of readmission and mortality in adults with diabetes or stress hyperglycemia after initial hospitalization for COVID-19.

BMJ open diabetes research & care·2024

A novel compound from neem leaves shows antifeedant properties against Spodptera litura. Its molecular structure is similar to other neem compounds and forms hydrogen bonds.

Area of Science:

  • Natural Product Chemistry
  • Entomology
  • Organic Chemistry

Background:

  • Azadirachta indica (neem) is a source of bioactive compounds.
  • Neem derivatives have demonstrated insecticidal and antifeedant properties.
  • Understanding the chemical structures and activities of neem compounds is crucial for developing natural pesticides.

Purpose of the Study:

  • To isolate and characterize a novel compound from the green leaves of Azadirachta indica.
  • To evaluate the antifeedant activity of the isolated compound against Spodptera litura.
  • To compare the molecular conformation with related known compounds.

Main Methods:

  • Isolation of the title compound from uncrushed green leaves of Azadirachta indica.
  • Chemical characterization of the isolated compound (C(32)H(42)O(8)).

Related Experiment Videos

  • Bioassays to determine antifeedant activity against Spodptera litura.
  • Conformational analysis and comparison with 3-desacetylsalannin.

    • Main Results:

    • A novel compound, methyl (2aS,3R,5R,5aS,6S,6aS,8R,9aS,10aR,10bR,10cS)-8-(3-furyl)-2a,4,5,5a,6,6a,8,9,9a,10a,10b,10c-dodecahydro-3-hydroxy-2a,5a,6a,7-tetramethyl-5-(3-methylbut-2-enoyloxy)-2H,3H-cyclopenta[4',5']furo[2',3':6,5]benzo[cd]isobenzofuran-6-acetate, was successfully isolated.
    • The isolated compound exhibited significant antifeedant activity against Spodptera litura.
    • The functional group conformations were found to be similar to 3-desacetylsalannin, with intermolecular hydrogen bonding observed.

    Conclusions:

    • The novel compound from neem leaves possesses potent antifeedant properties, offering potential as a natural pest control agent.
    • Structural similarities to known neem compounds suggest a conserved mechanism of action.
    • The study contributes to the understanding of neem's chemical diversity and its application in agriculture.