Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Exercise, cachexia, and cancer therapy: a molecular rationale.

C Murray Ardies1

  • 1Northeastern Illinois University, Chicago, IL 60625, USA. cmardies@neiu.edu

Nutrition and Cancer
|November 6, 2002
PubMed
Summary

Regular physical exercise offers a low-risk therapy for cancer patients, significantly improving daily activities and overall quality of life. Exercise may also mitigate treatment side effects and reduce secondary cancer risks through biological pathway modulation.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Inflammation as cause for scar cancers of the lung.

Integrative cancer therapies·2004
See all related articles

Area of Science:

  • Oncology
  • Exercise Physiology
  • Molecular Biology

Background:

  • Recent publications suggest exercise benefits cancer patients.
  • Physical activity may enhance quality of life and daily functioning.
  • Lack of negative effects supports exercise as a low-risk therapy.

Purpose of the Study:

  • To explore the benefits of repeated physical exercise for cancer patients.
  • To understand the mechanisms by which exercise impacts cancer rehabilitation.
  • To investigate exercise's role in attenuating adverse effects and reducing secondary cancer risk.

Main Methods:

  • Review of recent publications on exercise and cancer.
  • Analysis of molecular pathways influenced by physical activity.
  • Investigation of inflammatory responses and metabolic changes.

Related Experiment Videos

Main Results:

  • Physical exercise enhances quality of life and capacity for daily activities.
  • Exercise may prevent or reverse cachexia and reduce secondary cancer risk.
  • Mechanisms include attenuation of inflammation and activation of specific cellular pathways (e.g., MAPK, NF-κB).

Conclusions:

  • Repeated physical exercise is a promising low-risk therapy for cancer patients.
  • Exercise positively impacts cancer rehabilitation by modulating biological processes.
  • Further molecular research can illuminate cancer rehabilitation and endogenous risk mechanisms.