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Updated: Sep 28, 2026

Chromogenic In Situ Hybridization as a Tool for HPV-Related Head and Neck Cancer Diagnosis
Published on: June 14, 2019
[Cervical cancer screening by Pap smear: experience of the National Research Center in Reproductive Health. ONFP]
Rim Ben Aissa1, Ramzy Bennour, Abdelmajid Ben Hamida
1Office National de la Famille et de la Population Centre d'Etude et de Recherche en Santé Reproductive de l'Ariana 2, Rue Tahar Ben Ezzeddine 2080 Ariana, Tunisie.
Abstract:
We have analysed the result of 17,173 pap smears screened in the national research center in reproductive health of Ariana from 1 may 1993 to 30 april 1997. Among these pap smears, 613 colposcopy and 380 biopsy have been performed. The results show that: 1.9% of pap smears present cytological anomalies with 0.79% of low Squamous Intraepithelial lesions and 0.66% high Squamous Intraepithelial lesions. The incidence of CIN III is 1.8% and 0.9% for invasive cancer. The age interval 35-44 years is at high risk of CIN III and invasive cancer of the cervix. evaluation of our diagnostic approach shows that: positive predictive value of pap smears with low SLI is 43.2% positive predictive value of pap smears with high SLI is 37.3%.