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Vitamin intervention for stroke prevention
1Stroke Research Center, Wake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157-1068, USA. jtoole@wfubmc.edu
Journal of the Neurological Sciences
|November 6, 2002
Summary
This study investigates if folic acid and B vitamins prevent recurrent strokes. Results are pending but aim to support stroke prevention strategies.
Area of Science:
- Neurology
- Nutritional Science
- Preventive Medicine
Background:
- Recurrent stroke poses a significant health risk.
- Folic acid and B vitamins are studied for their potential role in vascular health.
- Risk factor reduction is a standard approach in stroke management.
Purpose of the Study:
- To determine if high-dose folic acid, vitamin B6, and vitamin B12 supplementation reduces recurrent stroke risk.
- To evaluate the efficacy of vitamin intervention alongside other preventive measures.
Main Methods:
- The Vitamin Intervention for Stroke Prevention (VISP) trial randomized 3,688 patients with a first-ever nondisabling stroke.
- Participants were assigned to either a high-dose or low-dose vitamin intervention group.
- Follow-up is ongoing to collect data on stroke recurrence.
Main Results:
- Case acquisition is complete with 3,688 participants enrolled.
- Data collection and follow-up are currently in progress.
- Final results are anticipated within the year.
Conclusions:
- The study is expected to provide evidence on the effectiveness of vitamin supplementation in preventing recurrent strokes.
- Findings from VISP may be comparable to the parallel VITATOPS study in Australia.
- Results will inform future stroke prevention guidelines.