Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Spatial and temporal influences on extinction.

Anthony Cate1, Marlene Behrmann

  • 1Department of Psychology, Carnegie Mellon University, Pittsburgh, PA 15213-3890, USA. acate@andrew.cmu.edu

Neuropsychologia
|November 6, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Large-scale functional overlap between dorsal and ventral object-responsive networks.

Research square·2026
Same author

Morphometrics of the preserved post-surgical hemisphere in pediatric drug-resistant epilepsy and implications for post-operative cognition.

Imaging neuroscience (Cambridge, Mass.)·2026
Same author

Colour blindness adversely impacts face recognition.

Visual cognition·2026
Same author

Visual agnosia in the era of behavioral and neural investigations.

Neuropsychologia·2025
Same author

The Emergence of Topography and Hemispheric Lateralization in High-Level Vision.

Quarterly journal of experimental psychology (2006)·2025
Same author

Bidirectional and asymmetric smooth pursuit deficits in childhood hemispherectomy patients.

Cortex; a journal devoted to the study of the nervous system and behavior·2025
Same journal

Prevalence and modulation of rat off-track head scanning on linear tracks: possible implications for representational and dynamic properties of hippocampal place cells.

Neuropsychologia·2026
Same journal

Identifying networks within an fMRI multivariate searchlight analysis.

Neuropsychologia·2026
Same journal

Modulating sentence comprehension in people with aphasia through anodal tDCS: A double-blind randomized cross-over study.

Neuropsychologia·2026
Same journal

Deficient processing of regularity violations during visuospatial neglect: a visual mismatch negativity study.

Neuropsychologia·2026
Same journal

Seeing is believing: mental imagery amplifies moral, emotional, and motivational responding to mentally constructed hypothetical events.

Neuropsychologia·2026
Same journal

From Past Recall to Future Projection: What Does Verb Tense Production Reveal About Mental Time Travel in Alzheimer's disease?

Neuropsychologia·2026
See all related articles

This study reveals spatial and temporal factors in attentional deficits like extinction. Predictability unexpectedly worsened extinction, supporting a neural gradient theory.

Area of Science:

  • Neuroscience
  • Cognitive Psychology
  • Clinical Neurology

Background:

  • Extinction is an attentional deficit where patients fail to report contralesional stimuli following ipsilesional stimuli.
  • Understanding the spatial and temporal dynamics of extinction is crucial for explaining underlying neural mechanisms.

Observation:

  • Two patients with extinction performed a visual identification task with varied stimulus locations and onset asynchrony (SOA).
  • Expectancy was manipulated by altering stimulus location predictability.
  • Performance was assessed based on the identification of contralesional and ipsilesional stimuli.

Findings:

  • Extinction was maximal when the contralesional stimulus followed the ipsilesional stimulus by 300-900 ms.
  • Spatial location influenced extinction, with reduced extinction when stimuli were more ipsilesional.

Related Experiment Videos

  • Increased extinction of contralesional stimuli occurred when stimulus location was predictable.

    • Implications:

    • Findings support a model of a contralesional-to-ipsilesional neural gradient with mutual inhibition.
    • This gradient may explain the spatial and temporal characteristics of attentional deficits in extinction.
    • The results offer insights into the neural basis of attention and its disorders.