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Did tRNA synthetase classes arise on opposite strands of the same gene?
Molecular Cell
|November 7, 2002
Abstract:
Structural homology of class II aminoacyl-tRNA synthetases to the HSP70 family and the existence of a gene whose sense and antisense strands code for a dehydrogenase and an HSP70 chaperonin justify reconsideration of a possible sense-antisense ancestry for the two synthetase classes.