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Related Concept Videos

Sequence Networks of Rotating Machines01:24

Sequence Networks of Rotating Machines

A Y-connected synchronous generator, grounded through a neutral impedance, is designed to produce balanced internal phase voltages with only positive-sequence components. The generator's sequence networks include a source voltage that is exclusively in the positive-sequence network. The sequence components of line-to-ground voltages at the generator terminals illustrate this configuration.
Zero-sequence current induces a voltage drop across the generator's neutral impedance and other...

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Related Experiment Video

Updated: Jul 10, 2026

Characterizing the Composition of Molecular Motors on Moving Axonal Cargo Using "Cargo Mapping" Analysis
11:09

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Published on: October 30, 2014

LINEs mobilize SINEs in the eel through a shared 3' sequence.

Masaki Kajikawa1, Norihiro Okada

  • 1Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Japan.

Cell
|November 7, 2002
PubMed
Summary

The eel genome

Area of Science:

  • Genomics
  • Molecular Biology
  • Retrotransposons

Background:

  • Long interspersed nuclear elements (LINEs) and short interspersed nuclear elements (SINEs) are mobile genetic elements.
  • LINEs and SINEs often share a co-dependent relationship for transposition.

Purpose of the Study:

  • To characterize eel LINE (UnaL2) and SINE (UnaSINE1) families.
  • To investigate the role of conserved 3' tails in UnaL2 retrotransposition and SINE mobilization.

Main Methods:

  • Bioinformatic analysis of eel genome.
  • Retrotransposition assays in HeLa cells.
  • Functional characterization of 3' tail elements.

Main Results:

  • UnaL2 and UnaSINE1 share similar 3' tails.

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Last Updated: Jul 10, 2026

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  • The conserved 3' tail of UnaL2 is essential for its retrotransposition.
  • UnaL2 reverse transcriptase recognizes UnaL2 and UnaSINE1 3' tails in trans.
  • Short 3' repeats of UnaL2 are crucial for retrotransposition.

    • Conclusions:

    • SINEs can be mobilized by the machinery of partner LINEs.
    • UnaL2 retrotransposition mechanism resembles telomerase reverse transcriptase activity.