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A novel t(2;3)(q31;p13) in acute myelocytic leukemia
1Department of Pathology, Queen Elizabeth Hospital, 30 Gascoigne Road, Kowloon, SAR, Hong Kong, China. kfwong@ha.org.hk
Cancer Genetics and Cytogenetics
|November 7, 2002
Abstract:
We report a case of acute myelocytic leukemia without maturation exhibiting a novel t(2;3)(q31;p13). Conventional cytogenetics showed the concomitant occurrence of a single metaphase with 47,XX,+8. Nevertheless, interphase cytogenetics by fluorescence in situ hybridization using a chromosome 8 alpha-satellite DNA probe showed that the percentage of cells with three hybridization signals was within the control range.