Maternal smoking during pregnancy and childhood obesity
Rüdiger von Kries1, André Michael Toschke, Berthold Koletzko
1Institute of Social Pediatrics and Adolescent Medicine, Ludwig Maximilian University of Munich, Munich, Germany. ag.epi@LRZ.uni-muenchen.de
Insights
Maternal smoking during pregnancy is linked to higher risks of childhood overweight and obesity. This study found a dose-dependent relationship, indicating that increased smoking by mothers during pregnancy raises the likelihood of these conditions in children.
Area of Science:
- Pediatrics
- Public Health
- Epidemiology
Background:
- Maternal smoking during pregnancy is a known risk factor for adverse child health outcomes.
- Childhood obesity is a growing public health concern with long-term health implications.
Purpose of the Study:
- To investigate the association between maternal smoking during pregnancy and the risk of childhood overweight and obesity.
- To determine if there is a dose-dependent relationship between smoking intensity and childhood obesity risk.
Main Methods:
- A cohort study utilizing data from school entry health examinations in Bavaria, Germany (1999-2000).
- Included 6,483 German children aged 5.00-6.99 years.
- Defined overweight (BMI > 90th percentile) and obesity (BMI > 97th percentile).
- Assessed maternal smoking habits during pregnancy as the primary exposure.
Main Results:
- Prevalence of overweight and obesity increased with maternal smoking levels: never smoked, <10 cigarettes/day, and ≥10 cigarettes/day.
- Adjusted odds ratios were 1.43 for overweight and 2.06 for obesity in children of mothers who smoked during pregnancy.
- A dose-dependent association was observed, with higher smoking levels correlating with increased risk.
Conclusions:
- Maternal smoking during pregnancy is significantly associated with an increased risk of childhood overweight and obesity.
- The findings suggest that intrauterine exposure to smoke products, rather than lifestyle factors, is the likely cause.
- Public health interventions targeting smoking cessation during pregnancy are crucial for preventing childhood obesity.
Abstract:
A recent cohort study suggested that maternal smoking during pregnancy might be a risk factor for childhood obesity. Data from the obligatory school entry health examination in six Bavarian (Germany) public health offices in 1999-2000 were used to assess the relation between maternal smoking during pregnancy and childhood obesity (n = 6,483 German children aged 5.00-6.99 years). A body mass index greater than the 90th percentile was defined as overweight, and a body mass index greater than the 97th percentile was defined as obesity. The main exposure was maternal smoking during pregnancy. The prevalences of overweight and obesity, expressed as percentages, increased in the following order: never smoked (overweight: 8.1, 95% confidence interval (CI): 7.2, 9.0; obesity: 2.2, 95% CI: 1.7, 2.7); less than 10 cigarettes daily (overweight: 14.1, 95% CI: 11.1, 17.7; obesity: 5.7, 95% CI: 3.7, 8.2); and 10 or more cigarettes daily (overweight: 17.0, 95% CI: 10.1, 26.2; obesity: 8.5, 95% CI: 3.7, 16.1). The adjusted odds ratios for maternal smoking during pregnancy were 1.43 (95% CI: 1.07, 1.90) for overweight and 2.06 (95% CI: 1.31, 3.23) for obesity. A dose-dependent association between overweight/obesity and maternal smoking during pregnancy was observed that could not be explained by a wide range of confounders, suggesting that intrauterine exposure to inhaled smoke products rather than lifestyle factors associated with maternal smoking accounts for this finding.
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