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Neuropathologic effects of intrathecal water
Journal of Neuropathology and Experimental Neurology
|September 1, 1975
Summary
Intrathecal distilled water infusion can cause significant neuropathologic changes in spinal roots and the spinal cord. These lesions, including axonal breakdown and neuronal damage, depend on the volume infused and survival time.
Area of Science:
- Neuropathology
- Neuroscience
- Oncology
Background:
- Intrathecal agents are used for pain management in disseminated carcinoma.
- Distilled water has been used as an intrathecal agent.