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Retroperitoneal extraskeletal mesenchymal chondrosarcoma in a dog
John S Munday1, Annalisa Prahl
1Department of Veterinary Pathology, College of Veterinary Medicine, University of Georgia, Athens 30602, USA.
Summary
A rare canine chondrosarcoma in a Mastiff dog showed distant metastases, a first for this extraskeletal mesenchymal chondrosarcoma (EMC) type. This tumor type is linked to a poor prognosis, especially in younger dogs.
Area of Science:
- Veterinary Pathology
- Canine Oncology
- Tumor Biology
Background:
- Extraskeletal mesenchymal chondrosarcomas (EMCs) are rare canine tumors.
- Previous reports indicate EMCs predominantly affect young dogs (under 3 years).
Observation:
- A young adult female Mastiff presented with a large retroperitoneal mass, pleural effusion, and multiple pulmonary and pleural nodules.
- Histological and immunohistochemical analyses confirmed mesenchymal subtype chondrosarcomas in all affected sites.
Findings:
- This case represents the first documented instance of distant metastasis in canine extraskeletal mesenchymal chondrosarcomas.
- The tumor exhibited aggressive behavior with widespread dissemination.
Implications:
- The findings highlight the aggressive potential of canine EMCs, including their capacity for distant metastasis.
- This case underscores the poor prognosis associated with EMCs, particularly when metastasis is present.